Testosterone undecanoate soft gel capsules, which include the brand name Jatenzo in the United States, are used to treat adult men with specific types of male hypogonadism. It is not used for "age-related hypogonadism". Who should take testosterone undecanoateTestosterone undecanoate is prescribed to men who have clinically confirmed low or absent endogenous testosterone due to specific medical conditions. These conditions are classified as:
- Primary hypogonadism: Caused by problems with the testes, such as testicular failure from genetics (e.g., Klinefelter syndrome), injury, surgery, infection, or chemotherapy. In these men, testosterone is low, and other hormone levels (FSH and LH) are elevated.
- Hypogonadotropic hypogonadism (secondary hypogonadism): Caused by issues with the hypothalamus or pituitary gland, which regulate hormone production. In these men, testosterone levels are low, and FSH and LH levels are low or normal.
Therapeutic effectsBy restoring testosterone to normal levels, this medication can help improve symptoms related to low testosterone, such as:
- Maintaining male sexual characteristics, including a deep voice and body hair.
- Improving sexual function and libido.
- Increasing muscle mass and strength.
- Boosting energy and overall vitality.
- Enhancing mood and addressing depressive symptoms.
- Preventing bone loss and treating osteoporosis caused by low testosterone.
Important considerations
- Not for age-related decline: Due to the risk of increased blood pressure and major adverse cardiovascular events (such as heart attack or stroke), testosterone undecanoate is not approved for men with age-related hypogonadism.
- Cardiovascular risk: A boxed warning from the U.S. Food and Drug Administration (FDA) highlights the risk of blood pressure increases, especially in men with pre-existing cardiovascular disease.
- Regular monitoring: Your doctor will monitor your blood pressure and testosterone levels during treatment.
- Not for body-building: This medication should not be used by healthy individuals to enhance athletic performance or for body-building.
- Potential side effects: Common side effects include headache, increased red blood cell count, diarrhea, burping, and high blood pressure. More serious side effects can also occur.Testosterone Undecanoate 40 mg Capsule is not recommended if you are allergic to it or have prostate or male breast cancer. Inform your doctor about all your current medications and existing medical conditions to make sure this medicine is safe for you. Use this medicine with caution if you have heart or liver problems. Testosterone Undecanoate 40 mg Capsule is not indicated for use in women. Testosterone Undecanoate 40 mg Capsule consists of a male sex hormone called Testosterone, which plays a crucial role in masculine growth, increasing muscle mass, boosting sexual drive, regulating fertility, etc. This medicine is used to treat various conditions caused by decreased testosterone levels in the body such as delayed puberty, impotence, loss of bone mass, erectile dysfunction (a condition where a man is unable to achieve and/or maintain an erection adequate for sexual intercourse), etc. It works by restoring the balance of testosterone hormone in the body.